クローン作成の現状
2015年1月27日
こんにちは。
皆さんは生物学者のガードン先生をご存知ですか? ガードン先生は２０１２年にノーベル生理医学賞を受賞された先生
現在、最高で胞胚まで発生させることができましたが、まだ幼生まで正常に成長させるまでにはいたっていません。インジェクターの操作になかなか慣れなくて大変
【キーワード】
*¹ クローン：遺伝的に同一である個体のこと
*² 単精受精：１つの卵に１つの精子が入って受精する方式
*³ 多精受精：１つの卵に多くの精子が入りその中から１つが選ばれ受精する受精
*⁴ ドナー核：核を提供する側のこと
*⁵ 割球：受精卵の受精膜を破りバラバラにした時に出てくる細胞
*⁶ レシピエント卵：核を提供される側の卵のこと
*⁷ 除核：核を取り除くこと
Hello. My name is Emma and I'm a first year Life Science course student. Today I'm going to explain the research I'm currently conducting into cloning*¹ fire-belly newts (cynops pyrrhogaster).
Sir John Bertrand Gurdon won the Nobel prize for Physiology and Medicine in 2012 using the nucleus of a cell from an African clawed frog (xenopus laevis). He was the first person to successfully clone a vertebrate. Following his lead, we are attempting to clone amphibians, in this case frogs, who use single precision fertilization*², and newts, who use polyspermy fertilization.*³ Specifically, we are trying to implant nuclei from the blastomeres*⁴ of fertilised eggs, called the donor*⁵, into the enucleated*⁶ unfertilized eggs of the recipients.*⁷ Although we haven't yet grown eggs to the laval stage, we have successfully grown the recipients' eggs*⁶ to the point of blastula. Getting used to using the injector is quite difficult but we are continually practicing and trying hard to get good results.
[Keywords]
*¹ clone: one individual that is genetically identical to another
*² single precision fertilization: a method of fertilisation whereby the egg is fertilised by a single sperm
*³ polyspermy fertilization: a method of fertilisation whereby the egg is fertilised by multiple sperms
*⁴ blastomere: a type of cell produced by cell division of a zygote after fertilisation
*⁵ donor: the individual which provides the genetic materialblastomere: a type of cell produced by cell division of a zygote after fertilisation
*⁶ enucleation: the process of removing the nucleus from a cell
投稿者: 日時: 16:59
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